A Study of Pyridostigmine in Postural Tachycardia Syndrome
Phase 2
50
about 19 years
15–55
1 site in MN
What this study is about
Researchers are testing whether pyridostigmine, a medication, improves tachycardia and stabilizes blood pressure in people with postural tachycardia syndrome (POTS). The trial will involve taking either placebo or 180 mg of pyridostigmine daily for three days. You will be randomly assigned to one group or the other. At each visit, you'll have medical exams, questionnaires about your symptoms, and some tests.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Placebo
- 2.Take pyridostigmine
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
pyridostigmine
Primary: Change in orthostatic symptoms using Composite Autonomic Symptom Scale (COMPASS) change
Secondary: Heart rate response to head-up tilt