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Study details
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Intra-articular Platelet-Rich Plasma vs. Viscosupplementation for Knee Osteoarthritis

Endeavor Health
NCT IDNCT03491761ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

100

Study length

about 9.6 years

Ages

18–75

Locations

1 site in IL

What this study is about

Researchers are testing whether platelet-rich plasma (PRP) is more effective than hyaluronic acid (HA) in treating knee osteoarthritis. The trial will measure changes in cartilage thickness and pain/function using the KOOS questionnaire to compare PRP and HA treatments.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive HA Treatment
  • 2.Receive PRP Treatment

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Cartilage Thickness on MRI

Body systems

Musculoskeletal