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Study details
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Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety

University of Cincinnati
NCT IDNCT04623099ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

132

Study length

about 5.7 years

Ages

12–17

Locations

1 site in OH

What this study is about

Researchers are testing whether a personalized approach to escitalopram dosing improves anxiety treatment in children. Participants will be randomly assigned to either standard or pharmacogenetically-guided escitalopram, based on their genetic makeup. The trial will last 2094 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Escitalopram

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

escitalopram (SSRI; increases serotonin availability)

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Tolerability-Activation

Body systems

Psychiatry / Mental Health