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Study details
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Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Northwestern University
NCT IDNCT05042258ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

40

Study length

about 1.4 years

Ages

6–17

Locations

1 site in IL

What this study is about

Researchers are testing if dupilumab can improve sleep, reduce itching (pruritus), and help with circadian rhythm problems in children with moderate to severe atopic dermatitis. The trial will involve giving children dupilumab for 12 weeks and then having them undergo overnight sleep studies before and after treatment.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Dupilumab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

dupilumab

Endpoints

Primary: PROMIS (Patient Reported Outcome Measurement Information System) parent-proxy score, PROMIS patient score

Body systems

Dermatology