Study details
Enrolling now
Extended Bolus for Meals in a Closed-loop System
University of California, San Francisco
NCT IDNCT05454891ClinicalTrials.gov data as of Apr 2026
Phase
Phase 4
Target enrollment
30
Study length
about 3.2 years
Ages
13–19
Locations
1 site in CA
What this study is about
This trial is testing whether giving more insulin at once (extended bolus) before meals, using a closed-loop system, can help control blood sugar levels better than standard insulin dosing. The goal is to see if the extended bolus helps prevent high or low blood sugar after eating.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Extended bolus of insulin then standard bolus of insulin
- 2.Receive Standard bolus of insulin then extended bolus of insulin
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IVInjection / IV
How treatment is administered
Treatment Assignment
Randomized (Open Label)
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug routes
injection
Endpoints
Primary: Glucose Area Under Curve [AUC]
Body systems
Endocrinology