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Study details
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Cardiac Rehabilitation for Building Exertional Heart Rate for Chronotropic Incompetence in Long COVID

University of California, San Francisco
NCT IDNCT05530317ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 2.8 years

Ages

18+

Locations

1 site in CA

What this study is about

Researchers are testing if cardiac rehabilitation improves exercise capacity and how well your heart responds to exercise among people with Long COVID. The trial will include adults who have symptoms of Long COVID that last at least 3 months after the initial infection, along with reduced exercise capacity and a poor heart rate response during cardiopulmonary exercise testing.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Cardiac Rehabilitation

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in adjusted heart rate reserve

Secondary: Change in Composite Autonomic Symptom Scale-31 (Compass 31) Score, Change in Generalized Anxiety Disorder Screener (GAD-7) Score, Change in Number of Long COVID symptoms, Change in Patient Health Questionnaire-9 (PHQ-9) Score, Change in Quality of life assessed with EuroQol (EQ-5D) Visual Analogue Scale, Change in Short Form Survey (SF-36) Score

Body systems

Infectious