Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
Phase 4
165
about 4.1 years
18–65
1 site in OK
What this study is about
This trial is testing whether the way people process threats in their brains differs between those with anxiety and depression, and how this affects their response to an anti-anxiety drug. It uses brain imaging to compare threat processing in individuals with comorbid anxiety and depression versus those with just depression or just anxiety.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo
- 2.Take Lorazepam
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
lorazepam
oral (Oral Tablet)
Psychiatry / Mental Health