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Study details
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Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

The University of Texas Health Science Center at San Antonio
NCT IDNCT06108076ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

10

Study length

about 2 years

Ages

18–80

Locations

1 site in TX

What this study is about

Researchers are testing whether oral ketones can affect heart function in people with heart failure, reduced ejection fraction, and type 2 diabetes. The trial will last for about a year and a half.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Ketone Monoester (KE)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Glucose, Patient Reported Outcomes Measure Information System (PROMIS) - Physical Function, Six minute walk test

Body systems

Endocrinology, Cardiology / Heart