Psilocybin rTMS for Treatment Resistant Depression
Phase 2
100
about 6 years
22–65
1 site in TX
What this study is about
This trial is testing whether giving psilocybin after a short, brain stimulation treatment (aiTBS) can help people with depression that hasn't responded to other treatments. The goal is to see if this combination is safe and works.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Low-dose psilocybin
- 2.Take Psilocybin
- 3.Use Accelerated intermittent theta burst (aiTBS) rTMS treatment
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
oral
Primary: Montgomery Asberg Depression Rating Scale (MADRS)
Secondary: Beck Depression Inventory II (BDI II), Columbia-Suicide Severity Rating Scale (C-SSRS), Discontinuation Emergent Signs and Symptoms Scale, Generalized Anxiety Disorder 7 (GAD-7), Mood and Anxiety Symptom Questionnaire 30 item Anhedonic Depression subscale (MASQ-30), Mood and Anxiety Symptom Questionnaire 30 item Anxious Arousal subscale (MASQ-30), Physicians Health Questionnaire 9 (PHQ-9), Quick Inventory of Depressive Symptom Self-Report (QIDS-SR)
therapeutic
Psychiatry / Mental Health