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Study details
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Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis

Yale University
NCT IDNCT06375811ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

297

Study length

about 2.5 years

Ages

18–40

Sex

Female only

Locations

5 sites in CO, CT, IL +2

What this study is about

This trial is testing whether taking a GnRH antagonist before IVF improves the chance of having a baby in women with endometriosis. The treatment involves taking Elagolix or a placebo, and comparing it to standard care (SOC) IVF.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo or SOC IVF
  • 2.Take Elagolix 200 MG

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

elagolix

Drug routes

oral (Oral Tablet)

Body systems

Reproductive Health