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Study details
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A Study to Evaluate the Effect of Bimekizumab on Gene Expression Biomarkers in Study Participants With Moderate to Severe Plaque Psoriasis

UCB Biopharma SRL
NCT IDNCT06506916ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

90

Study length

about 3.6 years

Ages

18+

Locations

7 sites in AL, CA, FL +3

What this study is about

Researchers are testing a treatment called bimekizumab to see how it affects gene expression markers in people with moderate to severe plaque psoriasis. The trial will last for 1324 days and involve approximately 90 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take bimekizumab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

bimekizumab

Endpoints

Primary: Change from Baseline in composite gene expression score using reverse transcription-polymerase chain reaction (RT-PCR) in lesional skin at Week 48

Secondary: TEAEs leading to permanent discontinuation of IMP from Baseline to the end of the SFU, Treatment-emergent adverse events (TEAEs) from Baseline to the end of the Safety Follow-Up (SFU), Treatment-emergent serious adverse event (TESAEs) from Baseline to the end of the SFU

Body systems

Dermatology