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Study details
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Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

University of California, San Diego
NCT IDNCT06586281ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 1.5 years

Ages

All ages

Locations

1 site in CA

What this study is about

Researchers are testing whether a treatment called guselkumab can help people with psoriasis who also have nonalcoholic fatty liver disease (NAFLD) improve their joint pain, skin problems, and liver health. The trial will last for 548 days and involve approximately 20 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Guselkumab

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

guselkumab

Drug routes

injection, intravenous

Endpoints

Secondary: Change from baseline in skin psoriasis severity, Change in ALT Levels

Body systems

Dermatology