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Study details
Enrolling now

Mechanical Alignment vs. Kinematic Alignment Total Knee Arthroplasty

Northwestern University
NCT IDNCT06617871ClinicalTrials.gov data as of Apr 2026
Target enrollment

95

Study length

about 4.4 years

Ages

21–79

Locations

1 site in IL

What this study is about

This trial is testing whether mechanical alignment (MA) or kinematic alignment (KA) is better for total knee arthroplasty (TKA). The goal is to compare these two approaches to see if one leads to better outcomes than the other.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Undergo Kinematic Alignment (KA) Interventions
  • 2.Undergo Mechanical Alignment (MA)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Body systems

Musculoskeletal