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Study details
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Cocoa Extract for Migraine Trial

Brigham and Women's Hospital
NCT IDNCT06808230ClinicalTrials.gov data as of Apr 2026
Target enrollment

114

Study length

about 1.4 years

Ages

18+

Locations

1 site in MA

What this study is about

This trial is testing if cocoa extract can help with migraines. Participants will take either cocoa extract or a placebo daily and provide urine samples and answer questionnaires.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Cocoa extract
  • 2.Cocoa extract placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

Dermatological Agents (Immunologic Factor Interactions)

Endpoints

Primary: Adherence, Recruitment, Retention

Secondary: Adverse events, Allodynia Symptom Checklist, PROMIS-29, Reports of worsening of migraine symptoms

Body systems

Neurology