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Study details
Enrolling now

Self-regulation of Real-time fMRI Brain Activity in Chronic Pain

Brigham and Women's Hospital
NCT IDNCT07023523ClinicalTrials.gov data as of Apr 2026
Target enrollment

36

Study length

about 9 months

Ages

18–65

Locations

1 site in MA

What this study is about

This trial is testing if self-regulating brain activity can help people with fibromyalgia. Participants will use real-time fMRI neurofeedback to observe and control their own brain activity while using mental strategies to reduce pain. It involves MRI scans, neurofeedback tasks, and weekly sessions with a pain psychologist.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Cognitive Behavioral Therapy
  • 2.Participate in Disease Education

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Changes in brain activity in pain-associated regions such as vPCC/RSC

Secondary: Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS)

Procedures

therapy

Body systems

Musculoskeletal