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Study details
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A Study of Baricitinib for Delaying Type 1 Diabetes

Eli Lilly and Company
NCT IDNCT07222137ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

150

Study length

about 5.5 years

Ages

1–35

Locations

7 sites in FL, IA, KY +2

What this study is about

Researchers are testing if baricitinib can delay the onset of type 1 diabetes in people at high risk. The trial will last up to five years and involve approximately 150 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Baricitinib
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

baricitinib

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Change from Baseline in AUC Ratio (AUC C-peptide/AUC Glucose × 1000), Change from Baseline in Body Mass Index (BMI) Percentile, Change from Baseline in Glucose AUC, Change from Baseline in Glucose-Stimulated C-peptide Area Under the Curve (AUC), Change from Baseline in Height, Change from Baseline in Matsuda Index, Change from Baseline in Short Form 36 Version 2 Health Survey, Acute (SF-36v2), PK: Area Under the Concentration Versus Time Curve (AUC) of Baricitinib

Body systems

Endocrinology