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Study details
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A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Hoffmann-La Roche
NCT IDNCT07223697ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

120

Study length

about 7.1 years

Ages

18+

Locations

2 sites in MI, PA

What this study is about

Researchers are testing the safety and effectiveness of a treatment called Afimkibart (also known as RO7790121) for people with atopic dermatitis who have already taken part in other afimkibart clinical trials. The trial will last 2591 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Afimkibart

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Percentage of Participants with Adverse Events

Secondary: Change From Baseline (in Parent Study) in Eczema Area and Severity Index (EASI) Score at Each Visit, Change from Baseline (in the parent study) in Dermatology Life Quality Index (DLQI) at Each Visit, Change from Baseline (in the parent study) in Participant-Oriented Eczema Measure (POEM) at Each Visit, Percent Change From Baseline (in Parent Study) in EASI Score at Each Visit

Body systems

Dermatology